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| 2013 |
| Forming crosslinked peptidoglycan from synthetic Gram-negative Lipid II. Lebar MD, Lupoli TJ, Tsukamoto H, May JM, Walker S, Kahne DE. J Am Chem Soc 2013; 135:4632-5. | Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors. Gampe CM, Tsukamoto H, Doud EH, Walker S, Kahne D. J Am Chem Soc 2013; 135:3776-9. |
| The Escherichia coli Lpt Transenvelope Protein Complex for Lipopolysaccharide Export is Assembled Via Conserved Structurally Homologous Domains. Villa R, Martorana AM, Okuda S, Gourlay LJ, Nardini M, Sperandeo P, Deho G, Bolognesi M, Kahne D, Polissi A. J Bacteriol 2013 195:1100-8. |
| 2012 |
| Cytoplasmic ATP Hydrolysis Powers Transport of Lipopolysaccharide Across the Periplasm in E. coli. Okuda S, Freinkman E, Kahne D. Science 2012; 338:1214-7.
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| Distinct Single-Cell Morphological Dynamics under Beta-Lactam Antibiotics. Yao Z, Kahne D, Kishony R. Mol Cell 2012; 48:705-12.
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| Disulfide Rearrangement Triggered by Translocon Assembly Controls Lipopolysaccharide Export. Chng SS, Xue M, Garner RA, Kadokura H, Boyd D, Beckwith J, Kahne D. Science 2012; 337:1665-8.
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| Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli. Yao Z, Davis RM, Kishony R, Kahne D, Ruiz N. Proc Natl Acad Sci USA 2012; 109(38):E2561-8.
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| Regulated Assembly of the Transenvelope Protein Complex Required for Lipopolysaccharide Export. Freinkman E, Okuda S, Ruiz N, Kahne D. Biochemistry 2012; 51:4800-6.
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| Activation of the Escherichia coli Beta-Barrel Assembly Machine (Bam) Is Required for Essential Components to Interact Properly with Substrate. Ricci DP, Hagan CL, Kahne D, Silhavy TJ. Proc Natl Acad Sci USA 2012; 109(9): 3487-3491.
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| 2011 |
| Nine Enzymes are Required for Assembly of the Pacidamycin Group of Peptidyl Nucleoside Antibiotics. Zhang W, Ntai I, Bolla ML, Malcolmson SJ, Kahne D, Kelleher NL, Walsh CT. J Am Chem Soc 2011; 133(14): 5240-5243.
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| Primer Preactivation of Peptidoglycan Polymerases. Wang TS, Lupoli TJ, Sumida Y, Tsukamoto H, Wu Y, Rebets Y, Kahne DE, Walker S. J Am Chem Soc 2011; 133(22): 8528-8530.
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| N-Methylimidazolium Chloride-Catalyzed Pyrophosphate Formation: Application to the Synthesis of Lipid I and NDP-Sugar Donors. Tsukamoto H, Kahne D. Bioorg Med Chem Lett 2011; 21(17): 5050-5053.
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| Haloduracin Alpha Binds the Peptidoglycan Precursor Lipid II with 2:1 Stoichiometry. Oman TJ, Lupoli TJ, Wang TS, Kahne D, Walker S, van der Donk WA. J Am Chem Soc 2011; 133(44): 17544-17547.
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| Transpeptidase-Mediated Incorporation of d-Amino Acids into Bacterial Peptidoglycan. Lupoli TJ, Tsukamoto H, Doud EH, Wang T-SA, Walker S, Kahne D. J Am Chem Soc 2011; 133(28): 10748-10751.
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| Beta-Barrel Membrane Protein Assembly by the Bam Complex. Hagan CL, Silhavy TJ, Kahne D. Annu Rev Biochem 2011; 80( ): 189-210.
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| The Reconstituted Escherichia coli Bam Complex Catalyzes Multiple Rounds of Beta-Barrel Assembly. Hagan CL, Kahne D. Biochemistry 2011; 50(35): 7444-7446.
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| Modular Synthesis of Diphospholipid Oligosaccharide Fragments of the Bacterial Cell Wall and Their Use to Study the Mechanism of Moenomycin and Other Antibiotics. Gampe CM, Tsukamoto H, Wang T-SA, Walker S, Kahne D. Tetrahedron 2011; 67(51): 9771-9778.
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| The Complex that Inserts Lipopolysaccharide into the Bacterial Outer Membrane Forms a Two-Protein Plug-and-Barrel. Freinkman E, Chng SS, Kahne D. Proc Natl Acad Sci USA 2011; 108(6): 2486-2491.
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| Lipoprotein LptE Is Required for the Assembly of LptD by the Beta-Barrel Assembly Machine in the Outer Membrane of Escherichia coli. Chimalakonda G, Ruiz N, Chng SS, Garner RA, Kahne D, Silhavy TJ. Proc Natl Acad Sci USA 2011; 108(6): 2492-2497.
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| 2010 |
| A Three Enzyme Pathway for 2-Amino-3-hydroxycyclopent-2-enone Formation and Incorporation in Natural Product Biosynthesis. Zhang W, Bolla ML, Kahne D, Walsh CT. J Am Chem Soc 2010; 132(18): 6402-6411.
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| The Bacterial Cell Envelope. Silhavy TJ, Kahne D, Walker S. Cold Spring Harb Perspect Biol 2010; 2(5): a000414.
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| Design and Synthesis of Functionalized Trisaccharides as p53-Peptide Mimics. Sakurai K, Kahne D. Tetrahedron Lett 2010; 51(29): 3724-3727.
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| Nonconsecutive Disulfide Bond Formation in an Essential Integral Outer Membrane Protein. Ruiz N, Chng SS, Hiniker A, Kahne D, Silhavy TJ. Proc Natl Acad Sci USA 2010; 107(27): 12245-12250.
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| The Role of the Substrate Lipid in Processive Glycan Polymerization by the Peptidoglycan Glycosyltransferases. Perlstein DL, Andrew Wang T-S, Doud EH, Kahne D, Walker S. J Am Chem Soc 2010; 132(1): 48-49.
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| Lipoprotein Cofactors Located in the Outer Membrane Activate Bacterial Cell Wall Polymerases. Paradis-Bleau C, Markovski M, Uehara T, Lupoli TJ, Walker S, Kahne DE, Bernhardt TG. Cell 2010; 143(7): 1110-1120.
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| Reconstitution of Outer Membrane Protein Assembly from Purified Components. Hagan CL, Kim S, Kahne D. Science 2010; 328(5980): 890-892.
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| Development of an Activity Assay for Discovery of Inhibitors of Lipopolysaccharide Transport. Gronenberg LS, Kahne D. J Am Chem Soc 2010; 132(8): 2518-2519.
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| Functional and Structural Analysis of a Key Region of the Cell Wall Inhibitor Moenomycin. Fuse S, Tsukamoto H, Yuan Y, Wang TS, Zhang Y, Bolla M, Walker S, Sliz P, Kahne D. ACS Chem Biol 2010; 5(7): 701-711.
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| Characterization of theTwo-Protein Complex in Escherichia coli Responsible for Lipopolysaccharide Assembly at the Outer Membrane. Chng SS, Ruiz N, Chimalakonda G, Silhavy TJ, Kahne D. Proc Natl Acad Sci USA 2010; 107(12): 5363-5368.
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| Proteins Required for Lipopolysaccharide Assembly in Escherichia coli Form a Transenvelope Complex. Chng SS, Gronenberg LS, Kahne D. Biochemistry 2010; 49(22): 4565-4567.
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| 2009 |
| Using Biological Performance Similarity to Inform Disaccharide Library Design. Tanikawa T, Fridman M, Zhu W, Faulk B, Joseph IC, Kahne D, Wagner BK, Clemons PA. J Am Chem Soc 2009; 131(14): 5075-5083.
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| Transport of Lipopolysaccharide Across the Cell Envelope: The Long Road of Discovery. Ruiz N, Kahne D, Silhavy TJ. Nat Rev Microbiol 2009; 7(9): 677-683.
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| Complete Characterization of the Seventeen Step Moenomycin Biosynthetic Pathway. Ostash B, Doud EH, Lin C, Ostash I, Perlstein DL, Fuse S, Wolpert M, Kahne D, Walker S. Biochemistry 2009; 48(37): 8830-8841.
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| Studying a Cell Division Amidase Using Defined Peptidoglycan substrates. Lupoli TJ, Taniguchi T, Wang TS, Perlstein DL, Walker S, Kahne DE. J Am Chem Soc 2009; 131(51): 18230-18231.
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| Rapid Beta-Lactam-Induced Lysis Requires Successful Assembly of the Cell Division Machinery. Chung HS, Yao Z, Goehring NW, Kishony R, Beckwith J, Kahne D. Proc Natl Acad Sci USA 2009; 106(51): 21872-21877.
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| 2008 |
| Structural Analysis of the Contacts Anchoring Moenomycin to Peptidoglycan Glycosyltransferases and Implications for Antibiotic Design. Yuan Y, Fuse S, Ostash B, Sliz P, Kahne D, Walker S. ACS Chem Biol 2008; 3(7): 429-436.
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| Isolated Peptidoglycan Glycosyltransferases from Different Organisms Produce Different Glycan Chain Lengths. Wang TS, Manning SA, Walker S, Kahne D. J Am Chem Soc 2008; 130(43): 14068-14069.
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| Identification of Two Inner-Membrane Proteins Required for the Transport of Lipopolysaccharide to the Outer Membrane of Escherichia coli. Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ. Proc Natl Acad Sci USA 2008; 105(14): 5537-5542.
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| A Unifying Nitrososynthase Involved in Nitrosugar Biosynthesis. Hu Y, Al-Mestarihi A, Grimes CL, Kahne D, Bachmann BO. J Am Chem Soc 2008; 130(47): 15756-15757.
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| 2007 |
| Synthesis of Heptaprenyl-Lipid IV to Analyze Peptidoglycan Glycosyltransferases. Zhang Y, Fechter EJ, Wang TS, Barrett D, Walker S, Kahne DE. J Am Chem Soc 2007; 129(11): 3080-3081.
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| Crystal Structure of a Peptidoglycan Glycosyltransferase Suggests a Model for Processive Glycan Chain Synthesis. Yuan Y, Barrett D, Zhang Y, Kahne D, Sliz P, Walker S. Proc Natl Acad Sci USA 2007; 104(13): 5348-5353.
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| Defining the Roles of the Periplasmic Chaperones SurA, Skp, and DegP in Escherichia coli. Sklar JG, Wu T, Kahne D, Silhavy TJ. Genes Dev 2007; 21(19): 2473-2484.
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| Lipoprotein SmpA Is a Component of the YaeT Complex that Assembles Outer Membrane Proteins in Escherichia coli. Sklar JG, Wu T, Gronenberg LS, Malinverni JC, Kahne D, Silhavy TJ. Proc Natl Acad Sci USA 2007; 104(15): 6400-6405.
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| The Direction of Glycan Chain Elongation by Peptidoglycan Glycosyltransferases. Perlstein DL, Zhang Y, Wang TS, Kahne DE, Walker S. J Am Chem Soc 2007; 129(42): 12674-12675.
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| Characterization of Rhodosaminyl Transfer by the AknS/AknT Glycosylation Complex and Its Use in Reconstituting the Biosynthetic Pathway of Aclacinomycin A. Leimkuhler C, Fridman M, Lupoli T, Walker S, Walsh CT, Kahne D. J Am Chem Soc 2007; 129(34): 10546-10550.
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| Structure and Function of an Essential Component of the Outer Membrane Protein Assembly machine. Kim S, Malinverni JC, Sliz P, Silhavy TJ, Harrison SC, Kahne D. Science 2007; 317(5840): 961-964.
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| Kinetic Analysis of Teicoplanin Glycosyltransferases and Acyltransferase Reveal Ordered Tailoring of Aglycone Scaffold to Reconstitute Mature Teicoplanin. Howard-Jones AR, Kruger RG, Lu W, Tao J, Leimkuhler C, Kahne D, Walsh CT. J Am Chem Soc 2007; 129(33): 10082-10083.
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| Chemoenzymatic Formation of Novel Aminocoumarin Antibiotics by the Enzymes CouN1 and CouN7. Fridman M, Balibar CJ, Lupoli T, Kahne D, Walsh CT, Garneau-Tsodikova S. Biochemistry 2007; 46(28): 8462-8471.
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| Analysis of Glycan Polymers Produced by Peptidoglycan Glycosyltransferases. Barrett D, Wang TS, Yuan Y, Zhang Y, Kahne D, Walker S. J Biol Chem 2007; 282(44): 31964-31971.
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| 2006 |
| Identification of a Protein Complex that Assembles Lipopolysaccharide in the Outer Membrane of Escherichia coli. Wu T, McCandlish AC, Gronenberg LS, Chng SS, Silhavy TJ, Kahne D. Proc Natl Acad Sci USA 2006; 103(31): 11754-11759.
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| The Total Synthesis of Moenomycin A. Taylor JG, Li X, Oberthur M, Zhu W, Kahne DE. J Am Chem Soc 2006; 128(47): 15084-15085.
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| Crystallographic Analysis of an 8-mer p53 Peptide Analogue Complexed with MDM2. Sakurai K, Schubert C, Kahne D. J Am Chem Soc 2006; 128(34): 11000-11001.
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| Probing the Barrier Function of the Outer Membrane with Chemical Conditionality. Ruiz N, Wu T, Kahne D, Silhavy TJ. ACS Chem Biol 2006; 1(6): 385-395.
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| Advances in Understanding Bacterial Outer-Membrane Biogenesis. Ruiz N, Kahne D, Silhavy TJ. Nat Rev Microbiol 2006; 4(1): 57-66.
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| Detection of Bacterial Toxins with Monosaccharide Arrays. Ngundi MM, Taitt CR, McMurry SA, Kahne D, Ligler FS. Biosens Bioelectron 2006; 21(7): 1195-1201.
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| YfiO Stabilizes the YaeT Complex and Is Essential for Outer Membrane Protein Assembly in Escherichia coli. Malinverni JC, Werner J, Kim S, Sklar JG, Kahne D, Misra R, Silhavy TJ. Mol Microbiol 2006; 61(1): 151-164.
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| Installation of the Pyrrolyl-2-carboxyl Pharmacophore by CouN1 and CouN7 in the Late Biosynthetic Steps of the Aminocoumarin Antibiotics Clorobiocin and Coumermycin A1. Garneau-Tsodikova S, Stapon A, Kahne D, Walsh CT. Biochemistry 2006; 45(28): 8568-8578.
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| Degradation and Reconstruction of Moenomycin A and Derivatives: Dissecting the Function of the Isoprenoid Chain. Adachi M, Zhang Y, Leimkuhler C, Sun B, LaTour JV, Kahne DE. J Am Chem Soc 2006; 128(43): 14012-14013.
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| 2005 |
| In Vitro Reconstitution of EryCIII Activity for the Preparation of Unnatural Macrolides. Yuan Y, Chung HS, Leimkuhler C, Walsh CT, Kahne D, Walker S. J Am Chem Soc 2005; 127(41): 14128-14129.
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| Identification of a Multicomponent Complex Required for Outer Membrane Biogenesis in Escherichia coli. Wu T, Malinverni J, Ruiz N, Kim S, Silhavy TJ, Kahne D. Cell 2005; 121(2): 235-245.
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| Chemical Conditionality: A Genetic Strategy to Probe Organelle Assembly. Ruiz N, Falcone B, Kahne D, Silhavy TJ. Cell 2005; 121(2): 307-317.
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| Characterization of the Aminocoumarin Ligase SimL from the Simocyclinone Pathway and Tandem Incubation with NovM,P,N from the Novobiocin Pathway. Pacholec M, Freel Meyers CL, Oberthur M, Kahne D, Walsh CT. Biochemistry 2005; 44(12): 4949-4956.
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| A Systematic Investigation of the Synthetic Utility of Glycopeptide Glycosyltransferases. Oberthur M, Leimkuhler C, Kruger RG, Lu W, Walsh CT, Kahne D. J Am Chem Soc 2005; 127(30): 10747-10752.
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| AknT Is an Activating Protein for the Glycosyltransferase AknS in L-Aminodeoxysugar Transfer to the Aglycone of Aclacinomycin A. Lu W, Leimkuhler C, Gatto GJ, Jr., Kruger RG, Oberthur M, Kahne D, Walsh CT. Chem Biol 2005; 12(5): 527-534.
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| Glycosylation of Glycopeptides: A Comparison of Chemoenzymatic and Chemical Methods. Leimkuhler C, Chen Z, Kruger RG, Oberthür M, Lu W, Walsh CT, Kahne D. Tetrahedron-Asymmetr 2005; 16(2): 599-603.
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| Differential Inhibition of Staphylococcus aureus PBP2 by Glycopeptide Antibiotics. Leimkuhler C, Chen L, Barrett D, Panzone G, Sun B, Falcone B, Oberthur M, Donadio S, Walker S, Kahne D. J Am Chem Soc 2005; 127(10): 3250-3251.
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| Tailoring of Glycopeptide Scaffolds by the Acyltransferases from the Teicoplanin and A-40,926 Biosynthetic Operons. Kruger RG, Lu W, Oberthur M, Tao J, Kahne D, Walsh CT. Chem Biol 2005; 12(1): 131-140.
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| Glycopeptide and Lipoglycopeptide Antibiotics. Kahne D, Leimkuhler C, Lu W, Walsh C. Chem Rev 2005; 105(2): 425-448.
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| Comparison of Antigen Constructs and Carrier Molecules for Augmenting the Immunogenicity of the Monosaccharide Epithelial Cancer Antigen Tn. Kagan E, Ragupathi G, Yi SS, Reis CA, Gildersleeve J, Kahne D, Clausen H, Danishefsky SJ, Livingston PO. Cancer Immunol Immunother 2005; 54(5): 424-430.
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| Kinetic Characterization of the Glycosyltransferase Module of Staphylococcus aureus PBP2. Barrett D, Leimkuhler C, Chen L, Walker D, Kahne D, Walker S. J Bacteriol 2005; 187(6): 2215-2217.
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| 2004 |
| Use of a Retroinverso p53 Peptide as an Inhibitor of MDM2. Sakurai K, Chung HS, Kahne D. J Am Chem Soc 2004; 126(50): 16288-16289.
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| A Practical Method for the Stereoselective Generation of Beta-2-Deoxy Glycosyl Phosphates. Oberthur M, Leimkuhler C, Kahne D. Org Lett 2004; 6(17): 2873-2876.
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| Characterization of a Regiospecific Epivancosaminyl Transferase GtfA and Enzymatic Reconstitution of the Antibiotic Chloroeremomycin. Lu W, Oberthur M, Leimkuhler C, Tao J, Kahne D, Walsh CT. Proc Natl Acad Sci USA 2004; 101(13): 4390-4395.
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| AknK is an L-2-Deoxyfucosyltransferase in the Biosynthesis of the Anthracycline Aclacinomycin A. Lu W, Leimkuhler C, Oberthur M, Kahne D, Walsh CT. Biochemistry 2004; 43(15): 4548-4558.
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| Reconstitution and Characterization of a New Desosaminyl Transferase, EryCIII, from the Erythromycin Biosynthetic Pathway. Lee HY, Chung HS, Hang C, Khosla C, Walsh CT, Kahne D, Walker S. J Am Chem Soc 2004; 126(32): 9924-9925.
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| Stochastic Detection of Monovalent and Bivalent Protein-Ligand Interactions. Howorka S, Nam J, Bayley H, Kahne D. Angew Chem Int Ed Engl 2004; 43(7): 842-846.
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| Characterization of NovP and NovN: Completion of Novobiocin Biosynthesis by Sequential Tailoring of the Noviosyl Ring. Freel Meyers CL, Oberthur M, Xu H, Heide L, Kahne D, Walsh CT. Angew Chem Int Ed Engl 2004; 43(1): 67-70.
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| Assembly of Dimeric Variants of Coumermycins by Tandem Action of the Four Biosynthetic Enzymes CouL, CouM, CouP, and NovN. Freel Meyers CL, Oberthur M, Heide L, Kahne D, Walsh CT. Biochemistry 2004; 43(47): 15022-15036.
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| 2003 |
| Initial Characterization of Novobiocic Acid Noviosyl Transferase Activity of NovM in Biosynthesis of the Antibiotic Novobiocin. Freel Meyers CL, Oberthur M, Anderson JW, Kahne D, Walsh CT. Biochemistry 2003; 42(14): 4179-4189.
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| Vancomycin Analogues Active Against VanA-Resistant Strains Inhibit Bacterial Transglycosylase without Binding Substrate. Chen L, Walker D, Sun B, Hu Y, Walker S, Kahne D. Proc Natl Acad Sci USA 2003; 100(10): 5658-5663.
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| Overcoming Degeneracy in Carbohydrate Recognition. Basu A, Kahne D. Angew Chem Int Ed Engl 2003; 42(22): 2504-2506.
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| 2002 |
| Incorporation of Glucose Analogs by GtfE and GtfD from the Vancomycin Biosynthetic Pathway to Generate Variant Glycopeptides. Losey HC, Jiang J, Biggins JB, Oberthür M, Ye X-Y, Dong SD, Kahne D, Thorson JS, Walsh CT. Chem Biol 2002; 9(12): 1305-1314.
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| Biopolymers: Multifaceted Biopolymers. Eckstein F, Kahne D, Degrado WF. Curr Opin Chem Biol 2002; 6(6): 805-808.
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| The Structural Basis for Induction of VanB Resistance. Dong SD, Oberthur M, Losey HC, Anderson JW, Eggert US, Peczuh MW, Walsh CT, Kahne D. J Am Chem Soc 2002; 124(31): 9064-9065.
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| Structural Requirements for VanA Activity of Vancomycin Analogues. Chen Z, Eggert US, Dong SD, Shaw SJ, Sun B, LaTour JV, Kahne D. Tetrahedron 2002; 58(32): 6585-6594.
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| 2001 |
| Better Substrates for Bacterial Transglycosylases. Ye XY, Lo MC, Brunner L, Walker D, Kahne D, Walker S. J Am Chem Soc 2001; 123(13): 3155-3156.
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| Hybrid Glycopeptide Antibiotics. Sun B, Chen Z, Eggert US, Shaw SJ, LaTour JV, Kahne D. J Am Chem Soc 2001; 123(50): 12722-12723.
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| Determining Absolute Configuration in Flexible Molecules: A Case Study. Specht KM, Nam J, Ho DM, Berova N, Kondru RK, Beratan DN, Wipf P, Pascal RA, Jr., Kahne D. J Am Chem Soc 2001; 123(37): 8961-8966.
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| Tandem Action of Glycosyltransferases in the Maturation of Vancomycin and Teicoplanin Aglycones: Novel Glycopeptides. Losey HC, Peczuh MW, Chen Z, Eggert US, Dong SD, Pelczer I, Kahne D, Walsh CT. Biochemistry 2001; 40(15): 4745-4755.
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| Genetic Basis for Activity Differences between Vancomycin and Glycolipid Derivatives of Vancomycin. Eggert US, Ruiz N, Falcone BV, Branstrom AA, Goldman RC, Silhavy TJ, Kahne D. Science 2001; 294(5541): 361-364.
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| 2000 |
| Design of an Oligosaccharide Scaffold That Binds in the Minor Groove of DNA. Xuereb H, Maletic M, Gildersleeve J, Pelczer I, Kahne D. J Am Chem Soc 2000; 122(9): 1883-1890.
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| The Role of Hydrophobic Substituents in the Biological Activityof Glycopeptide Antibiotics. Kerns R, Dong SD, Fukuzawa S, Carbeck J, Kohler J, Silver L, Kahne D. J Am Chem Soc 2000; 122(50): 12608-12609.
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| Calicheamicinâˆ'DNA Recognition:  An Analysis of Seven Different Drugâˆ'DNA Complexes. Kalben A, Pal S, Andreotti AH, Walker S, Gange D, Biswas K, Kahne D. J Am Chem Soc 2000; 122(35): 8403-8412.
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| Hydrogen Abstraction on Photolysis of a Naphthocarborane. Bradley AZ, Link AJ, Biswas K, Kahne D, Schwartz J, JonesJr M, Zhu Z, Platz MS. Tetrahedron Lett 2000; 41(45): 8691-8694.
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| The Molecular Basis for Pyrimidine-Selective DNA Binding: Analysis of Calicheamicin Oligosaccharide Derivatives by Capillary Electrophoresis. Biswas K, Pal S, Carbeck JD, Kahne D. J Am Chem Soc 2000; 122(35): 8413-8420.
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| 1999 |
| Synthesis of Vancomycin from the Aglycon. Thompson C, Ge M, Kahne D. J Am Chem Soc 1999; 121(6): 1237-1244.
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| SmI2 Cleavage of Chromomycin A3 Sugars. Specht KM, Harris CR, Molander GA, Kahne D. Tetrahedron Lett 1999; 40(10): 1855-1856.
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| DNA-Binding Glycoconjugates. Kahne D, Silva D, Walker S. in. Bioorganic Chemistry: Carbohydrates, Hecht SM, Ed. Oxford University Press pp. 174-197.
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| Nonstatistical Binding of a Protein to Clustered Carbohydrates. Horan N, Yan L, Isobe H, Whitesides GM, Kahne D. Proc Natl Acad Sci USA 1999; 96(21): 11782-11786.
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| Scavenging Byproducts in the Sulfoxide Glycosylation Reaction: Application to the Synthesis of Ciclamycin 0. Gildersleeve J, Smith A, Sakurai K, Raghavan S, Kahne D. J Am Chem Soc 1999; 121(26): 6176-6182.
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| Vancomycin Derivatives that Inhibit Peptidoglycan Biosynthesis without Binding D-Ala-D-Ala. Ge M, Chen Z, Onishi HR, Kohler J, Silver LL, Kerns R, Fukuzawa S, Thompson C, Kahne D. Science 1999; 284(5413): 507-511.
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| 1998 |
| Sulfenate Intermediates in the Sulfoxide Glycosylation Reaction. Gildersleeve J, Pascal RA, Kahne D. J Am Chem Soc 1998; 120(24): 5961-5969.
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| Reconstruction of Vancomycin by Chemical Glycosylation of the Pseudoaglycon. Ge M, Thompson C, Kahne D. J Am Chem Soc 1998; 120(42): 11014-11015.
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| Modification of Sugar Part of Glycopeptide Antibiotic, Vancomycin. Fukuzawa S, Kerns R, Ge M, Kahne D. Conference Proceedings: Symposium on the Chemistry of Natural Products (Japan) 1998; 40( ): 151-156.
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| 1997 |
| Polyvalent Binding to Carbohydrates Immobilized on an Insoluble Resin. Liang R, Loebach J, Horan N, Ge M, Thompson C, Yan L, Kahne D. Proc Natl Acad Sci USA 1997; 94(20): 10554-10559.
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| Combinatorial Approaches to Carbohydrates. Kahne D. Curr Opin Chem Biol 1997; 1(1): 130-135.
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| Design of Compounds that Increase the Absorption of Polar Molecules. Bowe CL, Mokhtarzadeh L, Venkatesan P, Babu S, Axelrod HR, Sofia MJ, Kakarla R, Chan TY, Kim JS, Lee HJ, Amidon GL, Choe SY, Walker S, Kahne D. Proc Natl Acad Sci USA 1997; 94(22): 12218-12223.
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| 1996 |
| Generalizing Glycosylation:  Synthesis of the Blood Group Antigens Lea, Leb, and Lex Using a Standard Set of Reaction Conditions. Yan L, Kahne D. J Am Chem Soc 1996; 118(39): 9239-9248.
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| Cationic Facial Amphiphiles: A Promising Class of Transfection Agents. Walker S, Sofia MJ, Kakarla R, Kogan NA, Wierichs L, Longley CB, Bruker K, Axelrod HR, Midha S, Babu S, Kahne D. Proc Natl Acad Sci USA 1996; 93(4): 1585-1590.
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| Parallel Synthesis and Screening of a Solid Phase Carbohydrate Library. Liang R, Yan L, Loebach J, Ge M, Uozumi Y, Sekanina K, Horan N, Gildersleeve J, Thompson C, Smith A, Biswas K, Still WC, Kahne D. Science 1996; 274(5292): 1520-1522.
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| 1995 |
| p-Methoxybenzyl Ethers as Acid-Labile Protecting Groups in Oligosaccharide Synthesis. Yan L, Kahne D. Synlett 1995; 1995(SI): 523-524.
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| Sensitivity of Glycopeptide Conformation to Carbohydrate Chain Length. Liang R, Andreotti AH, Kahne D. J Am Chem Soc 1995; 117(41): 10395-10396.
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| Strategies for the Design of Minor Groove Binders: A Re-Evaluation Based on the Emergence of Site-Selective Carbohydrate Binders. Kahne D. Chem Biol 1995; 2(1): 7-12.
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| 1994 |
| Glycosylation on the Merrifield Resin Using Anomeric Sulfoxides. Yan L, Taylor CM, Goodnow R, Kahne D. J Am Chem Soc 1994; 116(15): 6953-6954.
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| NMR Characterization of Calicheamicin γ1I Bound to DNA. Walker SL, Andreotti AH, Kahne DE. Tetrahedron 1994; 50(5): 1351-1360.
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| Analysis of Hydroxylamine Glycosidic Linkages: Structural Consequences of the NO Bond in Calicheamicin. Walker S, Gupta V, Kahne D, Gange D. J Am Chem Soc 1994; 116(8): 3197-3206.
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| Hydrogen Bonding in Micelle Formation. Venkatesan P, Cheng Y, Kahne D. J Am Chem Soc 1994; 116(15): 6955-6956.
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| Use of Triethylene Glycol to Mimic Oligosaccharides: Design and Synthesis of a Ligand Based on Chromomycin A3. Silva DJ, Kraml CM, Kahne D. Bioorg Med Chem 1994; 2(11): 1251-1259.
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| Chromomycin A3 as a Blueprint for Designed Metal Complexes. Silva DJ, Kahne D, Kraml CM. J Am Chem Soc 1994; 116(6): 2641-2642.
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| Isomorphous Binding of Mercury-Substituted Thiosaccharides to Pertussis Toxin Crystals Yields Crystallographic Phases. Shigeta R, Jr., Forest K, Yan L, Kahne D, Schutt CE. Acta Cryst 1994; D50(Part 1): 71-74.
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| Concise Synthesis of the Calicheamicin Oligosaccharide Using the Sulfoxide Glycosylation Method. Kim SH, Augeri D, Yang D, Kahne D. J Am Chem Soc 1994; 116(5): 1766-1775.
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| 1993 |
| Structural Characterization of a Calicheamicin-DNA Complex by NMR. Walker S, Murnick J, Kahne D. J Am Chem Soc 1993; 115(18): 7954-7961.
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| Studies of the 2:1 Chromomycin A3-Mg2+ Complex in Methanol: Role of the Carbohydrates in Complex Formation. Silva DJ, Kahne DE. J Am Chem Soc 1993; 115(18): 7962-7970.
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| The Sugars in Chromomycin A3 Stabilize the Mg2+-Dimer Complex. Silva DJ, Goodnow R, Jr., Kahne D. Biochemistry 1993; 32(2): 463-471.
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| A One Step Synthesis of the Ciclamycin Trisaccharide. Raghavan S, Kahne D. J Am Chem Soc 1993; 115(4): 1580-1581.
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| Direct Introduction of CH2OH by Intermolecular trapping of CO. Gupta V, Kahne D. Tetrahedron Lett 1993; 34(4): 591-594.
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| The Effects of Glycosylation on Peptide Backbone Conformation. Andreotti AH, Kahne D. J Am Chem Soc 1993; 115(8): 3352-3353.
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| 1992 |
| Cleavage Behavior of Calicheamicin γ1 and Calicheamicin T. Walker S, Landovitz R, Ding WD, Ellestad GA, Kahne D. Proc Natl Acad Sci USA 1992; 89(10): 4608-4612.
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| Facial Amphiphiles. Cheng Y, Ho DM, Gottlieb CR, Kahne D, Bruck MA. J Am Chem Soc 1992; 114(18): 7319-7320.
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| 1991 |
| Construction of Glycosidic N-O Linkages in Oligosaccharides. Yang D, Kim SH, Kahne D. J Am Chem Soc 1991; 113(12): 4715-4716.
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| Conformational Analysis of the Nitrogen-Oxygen Bond in the Calicheamicin Oligosaccharide. Walker S, Yang D, Kahne D, Gange D. J Am Chem Soc 1991; 113(12): 4716-4717.
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| 1990 |
| Sugars as DNA Binders: A Comment on the Calicheamicin Oligosaccharide. Walker S, Valentine KG, Kahne D. J Am Chem Soc 1990; 112(17): 6428-6429.
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| Preparation of the 4-Ethylamino Sugar of Calicheamicin: Assignment of Absolute Configuration. Kahne D, Yang D, Lee MD. Tetrahedron Lett 1990; 31(1): 21-22.
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| 1989 |
| Efficient Regio- and Stereocontrolled Synthesis of Highly Functionalized Polycyclic Systems Using the Diels-Alder Addition of Stannyl-Substituted Vinylketeneacetals. Stork G, Kahne D. Isr J Chem 1989; 29( ): 243.
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| Glycosylation of Unreactive Substrates. Kahne D, Walker S, Cheng Y, Van Engen D. J Am Chem Soc 1989; 111(17): 6881-6882.
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| 1988 |
| The Use of Alkoxy-Substituted Anomeric Radicals for the Construction of Beta-Glycosides. Kahne D, Yang D, Lim JJ, Miller R, Paguaga E. J Am Chem Soc 1988; 110(26): 8716-8717.
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| Hydrolysis of a Peptide Bond in Neutral Water. Kahne D, Still WC. J Am Chem Soc 1988; 110(22): 7529-7534.
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| 1984 |
| Substituent Effects on the Stereochemistry of Substituted Cyclohexanone Dimethylhydrazone Alkylations. An X-ray Crystal Structure of Lithiated Cyclohexanone Dimethylhydrazone. Collum DB, Kahne D, Gut SA, DePue RT, Mohamadi F, Wanat RA, Clardy J, Van Duyne G. J Am Chem Soc 1984; 106(17): 4865-4869.
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| 1983 |
| Stereocontrol in Homogeneous Catalytic Hydrogenation via Hydroxyl Group Coordination. Stork G, Kahne DE. J Am Chem Soc 1983; 105(4): 1072-1073.
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| 1981 |
| Kinetic Cyanations of Ketone Enolates. Kahne D, Collum DB. Tetrahedron Lett 1981; 22(50): 5011-5014.
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| 1980 |
| Sodium Permeability and Myocardial Resistance to Cell Swelling During Metabolic Blockade. Pine MB, Kahne D, Jaski B, Apstein CS, Thorp K, Abelmann WH. Am J Physiol Heart Circ Physiol 1980; 239(1): H31-H39.
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