Born:

Rugby (U.K.) April 28, 1935

Education:

Magdalen College School, Oxford, 1948-1953
Pilot Officer, Royal Air Force, 1953-1955
Sir Louis Stuart Exhibitioner, Balliol College, Oxford, 1955-1959
B.A., Final Honour School of Chemistry, 1959 (1st Class)
(Thesis: The role of hyperconjugation in aromatic substitution)
Harmsworth Scholar, Merton College, Oxford, 1959-1960
Research Lecturer, Christ Church, Oxford, 1960-1962
M.A., D.Phil, 1961 (Thesis: Intramolecular effects in aromatic systems)

Professional:

Postdoctoral Research Fellow, California Institute of Technology, 1961-1962
Visiting Lecturer, University of Illinois, Urbana, 1962
Fellow of Wadham College, Oxford, 1962-1974
Departmental Demonstrator, Dyson Perrins Laboratory, Oxford, 1962-1966
University Lecturer, University of Oxford, 1966-1974
Visiting Professor, Yale University, 1969 (Molecular Biophysics), 1971 (Chemistry)
Sloan Visiting Professor, Harvard University, 1973
Professor of Chemistry, Harvard University, 1974-
Amory Houghton Professor of Chemistry and Biochemistry, Harvard University, 1979-
Chairman, Department of Chemistry, Harvard University, 1980-1983
Dean of the Faculty of Arts and Sciences, Harvard University, 1991-2002
Dean of the Faculty of Arts and Sciences, Harvard University, 2006-2007

Honors:

Fellow of the Royal Society (London), 1977
Charmian Medal, Royal Society of Chemistry, 1981
Fellow of the American Academy of Arts and Sciences, 1982
Newton Abraham Visiting Professor, Oxford University, 1983-84
Honorary Fellow, Balliol College, Oxford, 1984
Kenner Prize, 1985
Foreign Associate, National Academy of Sciences, 1988
Member, American Philosophical Society, 1988
Guthikonda Award, 1988
Alfred Bader Award, 1989
Arthur Cope Scholar Award, 1989
Prelog Medal, 1989
Honorary Fellow, Wadham College, Oxford, 1990
Smissman Medal, 1990
Honorary Fellow, Royal Society of Chemistry (London), 1991
Davy Medal, Royal Society (London), 1991
Repligen Award, 1992
Doctor, honoris causa, University of Edinburgh, 1992
Commander of the British Empire (Queen's Birthday Honours), 1993
Robert A. Welch Award, 1995
Nakanishi Award, 1999
Doctor, honoris causa, Eidgenössische Technische Hochschule, Zürich, 2001
Harvard Medal, 2002
Harvard University Distinguished Service Professor, 2003

Named Lectureships:

Baker Lecture, University of California, Santa Barbara, 1978
Philips Lectures, Haverford College, Pennsylvania, 1978
Lutz Lecture, University of Virginia, 1980
Byron Riegel Lectures, Northwestern University, Illinois, 1980
Dreyfus Distinguished Lecturer, Vanderbilt University, 1981
Troy C. Daniels Lectures, University of California, San Francisco, 1982
Cassett Lecture, Temple University, Philadelphia, 1982
T. Y. Shen Lectures in Medicinal Chemistry, MIT, Cambridge, 1982
O. Hayaishi Plenary Lecture, 12th International Congress of Biochemistry, Perth, Australia, 1982
Keynote Lecturer, Western Central States Biochemistry Conference,Oklahoma, 1982
Camille and Henry Dreyfus Lecturer, California Institute of Technology, 1983
Plenary Lecturer, IUPAC International Symposium, Poznan, Poland, 1984
College of Science Lectures, University of Notre Dame, Indiana, 1985
George Kenner Lecture, University of Liverpool, U.K., 1985
Smith Kline & French Distinguished Lecturer, Pennsylvania, 1985
Ada Doisey Lecturer, University of Illinois, 1985
Kharasch Visiting Professor, University of Chicago, 1985
Calbiochem-Behring Lecturer, University of California, San Diego, 1986
Venable Lecturer, University of North Carolina, Chapel Hill, 1986
Cynthia Chan Memorial Lectures, University of California, Berkeley, 1986
Gerhard Schmidt Memorial Lecture, Weizmann Institute of Science, 1986
Hirschmann Lecture, Oberlin College, Ohio, 1986
Frontiers in Chemical Research Lectures, Texas A&M University, 1987
Romanes Lecture, University of Edinburgh, U.K., 1987
Mildred Cohn Lecture, University of Pennsylvania, 1987
Dauben Lecture, University of Washington, 1987
Sandin Lectures, University of Alberta, 1987
Chambers Memorial Lectures, University of Rochester, 1988
Barton Lecture, University of Oklahoma, 1988
Bernard Axelrod Lecture, Purdue University, 1988
Plenary Lecturer, Protein Structure and Enzyme Catalysis, Mosbach, 1988
Plenary Lecturer, joint meeting NZIC & NZBS, New Zealand, 1988
Guthikonda Memorial Lecture, Columbia University, 1988
Baker Lectures in Chemistry, Cornell University, 1988
W.S. Johnson Symposium in Organic Chemistry, Stanford University, 1988
Keynote Lecturer, UCLA Symposium on Protein and Pharmaceutical Engineering, 1989
Robbins Lecturer, Pomona College, 1989
Stein Memorial Lecturer, Rockefeller University, 1989
John Stauffer Distinguished Lecture, University of Southern California, 1989
Frontiers of Biological Science Lecturer, Case Western Reserve University, 1989
Kolthoff Lecturer, University of Minnesota, 1989
Leermakers Symposium Lecturer, Wesleyan University, 1989
Plenary Lecturer, Prospects in Protein Engineering, Groningen, 1989
Prelog Lecture, ETH, Zurich, 1989
Marker Lecturer, University of Maryland, 1990
Trends in Biochemistry and Molecular Biology, Torremolinos, Spain, 1990
Leslie Hellerman Memorial Lecturer, Johns Hopkins University, 1990
Plenary Lecturer, Frontiers in Enzyme Chemistry, University of Illinois, 1990
Syntex Lecturer, Colorado State University, 1990
Allergan Lecturer, University of California, Irvine, 1990
Linus Pauling Distinguished Lecturer, Oregon State University, 1990
Plenary Lecturer, Royal Society of Chemistry, Kent, U.K., 1990
Plenary Lecturer, Protein Society, San Diego, 1990
Smissman Lecturer, University of Kansas, 1990
Plenary Lecturer, Royal Society, London, U.K., 1990
Plenary Lecturer, Biosciencedays-90, Helsinki, 1990
Plenary Lecturer, Royal Society of Chemistry, University of Kent, 1990
Birch Lecturer, Canberra, Australia, 1991
Warner-Lambert Distinguished Lecturer, Michigan State University, 1991
A. R. Gordon Distinguished Lecturer, University of Toronto, 1991
Plenary Lecturer, 150th Anniversary Meeting, Royal Society of Chemistry, London, 1991
Distinguished Lecturer in Biochemistry & Molecular Biology, University of Wisconsin, Milwaukee, 1991
Rennebohm Lecturer, University of Wisconsin, Madison, 1991
Merck Lecturer, University of Cambridge, U.K., 1991
Pfizer Lecturer, Harvard University, 1992
Repligen Award Lecture, San Diego, 1992
Robert A. Welch Award Lecture, 1995
Nakanishi Award Lecture, Anaheim, 1999
Merck Lecturer, University of Cambridge, U.K., 2002

Publications:

More than 250 research articles, book chapters, and reviews in professional journals.
[Five most cited papers: "Enzyme-Catalyzed Phosphoryl Transfer Reactions" (Annu. Rev. Biochem. 49, 877 (1980)); "Evolution of Enzyme Function and the Development of Catalytic Efficiency" (Biochemistry, 15, 5631 (1976)); "Photogenerated Reagents for Biological Receptor-Site Labeling" (Acc. Chem. Res. 5, 155 (1972)); "Tinkering with Enzymes: What are We Learning?" (Science, 236, 1252 (1987)); and "Enzyme catalysis: not different, just better" (Nature, 350, 121 (1991)).]