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27. Total Syntheses of HMP-Y1, Hibarimicinone, and HMP-P1. Liau, B. B.; Milgram, B. C.; Shair, M. D. J. Am. Chem. Soc. 2012, 18, ASAP. link

ja-2012-07207q_0013


26. Gram-Scale Synthesis of the A'B'-Subunit of Angelmicin B. Milgram, B. C.; Liau, B. B.; Shair, M. D. Org. Lett.
2011, 13, 6436–6439. link



25. Natural Products Reveal Cancer Cell Dependence on Oxysterol-Binding Proteins. Burgett, A. W. G.; Poulsen, T. B.; Wangkanont, K.; Anderson, D. R.; Kikuchi, C.; Shimada, K.; Okubo, S.; Fortner, K. C.; Mimaki, Y.; Kuroda, M.; Murphy, J. P.; Schwalb, D. J.; Petrella, E. C.; Cornella-Taracido, I.; Schirle, M.; Tallarico, J. A.; Shair, M. D. Nature Chemical Biology
2011, 7, 639–647. link



24. Enantioselective Synthesis of the Lomaiviticin Aglycon Full Carbon Skeleton Reveals Remarkable Remote Substituent Effects during the Dimerization Event. Lee, H. G.; Ahn, J. Y.; Lee, A. S.; Shair, M. D. Chem. Eur. J. 2010, 16, 13058-13062. pdf



23. Synthesis of N-(tert-butyloxycarbonyl)-O-triisopropylsiyl-D-pyrrolosamine Glycal of Lomaiviticins A and B via Epimerization of L-Threonine. Morris, W. J.; Shair, M. D. Tetrahedron Lett. 2010, 51, 4310–4312. pdf



22. Total Synthesis of (+)-Fastigiatine. Liau, B. B.; Shair, M. D. J. Am. Chem. Soc. 2010, 132, 9594–9595. link



21. Enantioselective Synthesis of (+)-Cephalostatin 1. Fortner, D. C.; Kato, D.; Tanaka, Y.; Shair, M. D. J. Am. Chem. Soc. 2010, 132, 275–280. pdf



20. Stereoselective Synthesis of 2-Deoxy-ß-glycosides Using Anomeric O-Alkylation/Arylation. Morris, W. J.; Shair, M. D. Org. Lett. 2008, 11, 9–12. pdf



19. Enantioselective Synthesis of (+)-Cortistatin A, a Potent and Selective Inhibitor of Endothelial Cell Proliferation. Lee, H. M.; Nieto-Oberhuber, C.; Shair, M. D. J. Am. Chem. Soc.
2008, 130, 16864–16866. pdf



18. Enantioselective Synthesis of the Central Ring System of Lomaiviticin A in the Form of an Unusually Stable Cyclic Hydrate. Krygowski, E. S.; Murphy-Benenato, K.; Shair, M. D. Angew. Chem. Int. Ed. Engl. 2008, 47, 1680-1684. pdf



17. Syntheses of the Eastern Halves of Ritterazines B, F, G, and H, Leading to Reassignment of the 5,5-Spiroketal Stereochemistry of Ritterazines B and F. Phillips, S. T.; Shair, M. D. J. Am. Chem. Soc.
2007, 129, 6589-6598. pdf



16. Stereoelectronic Effects Dictate Mechanistic Dichotomy between Cu(II)-Catalyzed and Enzyme-Catalyzed Reactions of Malonic Acid Half Thioesters. Fortner, K. C.; Shair, M. D. J. Am. Chem. Soc.
2007, 129, 1032-1033. pdf



15. Synthesis of a 10,000-membered Library of Molecules Resembling Carpanone and Discovery of Vesicular Traffic Inhibitors.  Goess, B.; Hannoush, R.; Chan, L.; Kirchhausen, T.; Shair, M. D. J. Am. Chem. Soc.
2006, 128, 5391-5403. pdf



14. The Small Molecule Secramine Inhibits Cdc42-Dependent Functions in Cells and Cdc42 Activation In Vitro  Pelish, H. E.; Peterson, J. R.; Salvareeza, S. B.; Rodriquez-Boulan, E.; Nazef, N.; Annis, D. A.; Chen, J.-L.; Stamnes, M.; Feng, Y.; Shair, M. D.; Kirchhausen, T. Nature Chemical Biology
2005, 2, 39-46. pdf


13. Catalytic Enantioselective Thioester Aldol Reactions That Are Compatible With Protic Functional Groups.  Magdziak, D.; Lalic, G.; Lee, H. M.;  Fortner, K. C.; Aloise, A. D.; Shair, M. D.  J. Am. Chem. Soc. 2005, 127, 7284-7285. pdf



12. Dynamic Kinetic Resolution During a Cascade Reaction on Substrates with Chrial All-Carbon Quaternary Centers.  Xu, K.; Lalic, G.; Shair, M. D. Angew. Chem. Int. Ed. Engl. 
2005, 44, 2259-2261. pdf



11. Synthesis of (-)-longithorone A:  Using Organic Synthesis to Probe a Proposed Biosynthesis.  Morales, C. A.; Layton, M. E.; Shair, M. D.  Proc. Natl. Acad. Sci.
2004, 101, 33, 12036-12041. pdf

10. An Exceptionally Mild Catalytic Thioester Aldol Reaction Inspired by Polyketide Biosynthesis.  Lalic, G; Aloise, A. D.; Shair, M. D. J. Am. Chem. Soc.
2003, 125, 2852-2853. pdf



9. Biomimetic Synthesis of (-)-Longithorone A.  Layton, M. E.; Morales, C. M.; Shair, M. D. J. Am. Chem. Soc.
2002, 124, 773-775. pdf




8. Use of Biomimetic Diversity-Oriented Synthesis to Discover Galanthamine-Like Molecules with Biological Properties Beyond Those of the Natural Product.  Pelish, H. E.; Westwood, N. J.; Feng, Y.; Kirchhausen, T.; Shair, M. D.  J. Am. Chem. Soc.
2001, 123, 6740-6741. pdf

7. Reaction Microarrays:  A Method for Determining the Enantiomeric Excess of Thousands of Samples.  Korbel, G.; Lalic, G.; Shair, M. D.  J. Am. Chem. Soc.
2001, 123, 361-362. pdf

6. Synthesis of Cyclooctenones  Using Intramolecular Hydroacylation.  Aloise, A.; Layton, M. E.; Shair, M. D. J. Am. Chem. Soc.
2000, 122, 12610-12611. pdf

5. Synthesis of (+)-CP-263,114.  Chen, C.; Layton, M. E.; Sheehan, S. M.; Shair, M. D. J. Am. Chem. Soc.
2000, 122, 7424-7425. pdf

4. A Highly Efficient and Convergent Reaction for the Synthesis of Bridgehead Enone-Containing Polycyclic Ring Systems.  Sheehan, S. M.; Lalic, G.; Chen, J.; Shair, M. D.  Angew. Chem. Int. Ed. Engl. 
2000,  39, 2714-2715. pdf

3. Solid-Phase Biomimetic Synthesis of Carpanone-Like Molecules.  Lindsley, C; Chan, L.; Goess, B.; Joseph, R.; Shair, M. D. J. Am. Chem. Soc.
2000, 122, 422-423. pdf

2. Stereospecific Synthesis of the CP-263,114 Core Structure.  Chen, C.; Layton, M. E.; Shair, M. D. J. Am. Chem. Soc.
1998, 120, 10784-10785. pdf

1. A Closer View of an Oncoprotein-Tumor Suppressor Interaction.  Shair, M. D.  Chemistry and Biology,
1997, 4, 791. pdf