Chemistry 115 Handouts

Listed below are the latest PDF versions of the handouts used in Professor Myers' Chemistry 115 class, which is entitled "Advanced Organic Chemistry: Synthesis of Complex Molecules." The handouts cover many essential reactions widely used in modern organic synthesis, and they are arranged according to the order in which they were covered in class.

• Organolithium Reagents

• The Stille Reaction

• The Suzuki Reaction

• The Heck Reaction

• Asymmetric Alkylation

• Asymmetric Alkylation-Chiral Catalysts

• Asymmetric Allylation and Crotylation

• Stereoselective, Directed Aldol Reaction

• Horner-Wadsworth-Emmons Olefination

• Olefin Metathesis

• Sharpless Asymmetric Epoxidation Reaction

• Transformations of 2,3-Epoxy Alcohols

• Jacobsen Asymmetric Epoxidation Reaction

• Jacobsen Catalytic Asymmetric Epoxide-Opening Reactions

• Noyori Asymmetric Hydrogenation Reaction

• Sharpless Asymmetric Dihydroxylation Reaction

• Asymmetric Diels-Alder Reactions

• Oxidation 

•Directed Ortho Metalation 

• Reduction 

• Lithium-Halogen Exchange 

• Protective Groups - Silicon-Based Protection of the Hydroxyl Group 

Shi Asymmetric Epoxidation Reaction: pg1, pg2, pg3, pg4, pg5

Asymmetric Addition Reactions of Organozihc Reagents