The Saghatelian Lab


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Publications:
  1. Saghatelian, A.; Cravatt, B.F., Assignment of protein function in the postgenomic era. Nature Chemical Biology, 2005, 1, 130-142.
  2. Saghatelian, A.; Cravatt, B.F., Discovery metabolite profiling - forging functional connections between the proteome and metabolome. Life Sci., 2005, 77, 1759-1766.
  3. Saghatelian, A.; Cravatt, B.F., Global strategies to integrate proteome and metabolome. Curr. Opin. Chem. Biol., 2005, 9, 62-68.
  4. Saghatelian, A.; Trauger, S. A.; Want, E. J.; Hawkins, E. G.; Siuzdak, G.; Cravatt, B. F., Assignment of endogenous substrates to enzymes by global metabolite profiling. Biochemistry, 2004, 43, 14332-14339.
  5. Saghatelian, A.; Jessani, N.; Joseph, A.; Humphrey, M.; Cravatt, B. F., Activity-based probes for the proteomic profiling of metalloproteases. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 10000-10005.
  6. Cravatt, B. F.; Saghatelian, A.; Hawkins, E. G.; Clement, A. B.; Bracey, M. H.; Lichtman, A. H., Functional dissociation of the central and peripheral fatty acid amide signaling systems. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 10821-10826.
  7. Saghatelian, A.; Guckian, K. M.; Thayer, D. A.; Ghadiri, M. R., DNA detection and signal amplification via an engineered allosteric enzyme. J. Am. Chem. Soc. 2003, 125, 344-345.
  8. Saghatelian, A.; Yokobayashi, Y.; Soltani, K.; Ghadiri, M. R., A chiroselective peptide replicator. Nature 2001, 409, 797-801.
  9. Merlic, C. A.; Aldrich, C. C.; Albaneze-Walker, J.; Saghatelian, A.; Mammen, J., Total Synthesis of the Calphostins: Application of Fischer Carbene Complexes and Thermodynamic Control of Atropisomers. J. Org. Chem. 2001, 66, 1297-1309.
  10. Merlic, C. A.; Aldrich, C. C.; Albaneze-Walker, J.; Saghatelian, A., Carbene Complexes in the Synthesis of Complex Natural Products: Total Synthesis of the Calphostins. J. Am. Chem. Soc. 2000, 122, 3224-3225.