The Saghatelian Lab


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Selected Publications:
  1. Vinayavekhin N, Saghatelian A (2009). Regulation of Alkyl-dihydrothiazole-carboxylates (ATCs) by Iron and the Pyochelin Gene Cluster in Pseudomonas aeruginosa. ACS Chem Biol 4:617–623. PubMed.
  2. Tagore DM, Nolte WM, Neveu JM, Rangel R, Guzman-Rojas L, Pasqualini R, Arap W, Lane WS, Saghatelian A (2008). Peptidase Substrates via Global Peptide Profiling. Nat Chem Biol 5:23–25. PubMed.
  3. Tagore R, Thomas HR, Homan EA, Munawar A, Saghatelian A (2008). A Global Metabolite Profiling Approach to Identify Protein-Metabolite Interactions. J Am Chem Soc 130:14111–14113. PubMed.
  4. Saghatelian A, McKinney MK, Bandell M, Patapoutian A, Cravatt BF (2006). A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry 45:9007–9015. PubMed.
  5. Saghatelian A, Trauger SA, Want EJ, Hawkins EG, Siuzdak G, Cravatt BF (2004). Assignment of endogenous substrates to enzymes by global metabolite profiling. Biochemistry 43:14332–14339. PubMed.
  6. Saghatelian A, Jessani N, Joseph A, Humphrey M, Cravatt BF (2004). Activity-based probes for the proteomic profiling of metalloproteases. Proc Natl Acad Sci USA 101:10000–10005. PubMed.
  7. Cravatt BF, Saghatelian A, Hawkins EG, Clement AB, Bracey MH, Lichtman AH (2004). Functional dissociation of the central and peripheral fatty acid amide signaling systems. Proc Natl Acad Sci USA 101:10821–10826. PubMed.
  8. Saghatelian A, Yokobayashi Y, Soltani K, Ghadiri MR (2001). A chiroselective peptide replicator. Nature 409:797–801. PubMed.